Design and Synthesis of Polycyclic Imidazole‐Containing N‐ Heterocycles based on CH Activation/Cyclization Reactions
A new strategy for the synthesis of polycyclic imidazole‐containing N‐heterocycles, based on the two general synthetic ways, namely the Pd(II)‐catalyzed intramolecular arylation via CH/CHal and CH/CH coupling reactions, was developed. The method proposed here enables the synthesis of many fused N‐heterocycles containing purine, 1‐deazapurines and benzimidazole structural units.
Document Type: Research Article
Affiliations: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany, Fax: (+49)-381-498 6412
Publication date: September 17, 2012