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Design and Synthesis of Polycyclic Imidazole‐Containing N‐ Heterocycles based on CH Activation/Cyclization Reactions

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A new strategy for the synthesis of polycyclic imidazole‐containing N‐heterocycles, based on the two general synthetic ways, namely the Pd(II)‐catalyzed intramolecular arylation via CH/CHal and CH/CH coupling reactions, was developed. The method proposed here enables the synthesis of many fused N‐heterocycles containing purine, 1‐deazapurines and benzimidazole structural units.

Document Type: Research Article


Affiliations: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany, Fax: (+49)-381-498 6412

Publication date: 2012-09-17

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