Palladium‐Catalyzed and Hybrid Acids‐Assisted Synthesis of Fulleroazepines in One Pot under Mild Conditions: Annulation of
An extraordinarily efficient hybrid acids‐assisted, palladium‐catalyzed and chelating‐group‐assisted CH bond activation of N‐sulfonyl‐2‐aminobiaryls and their annulations with fullerene via sequential CC and CN bond formation at room temperature to afford fulleroazepines is demonstrated. The formation of fulleroazepines is highly regioselective and tolerant to both electron‐withdrawing and electron‐donating groups on the aryl moiety and the reaction gives monofunctionalized fullerenes in good yields (up to 54% isolated yield and 92% based on converted C60).
Document Type: Research Article
Affiliations: Department of Applied Chemistry, National Chiao Tung University, Hsinchu 30010, Taiwan, R.O.C. phone: (+886)-35731858, Fax: (+886)-35723764
Publication date: 2012-09-17