The Topographic Effect of Zinc Oxide Nanoflowers on Osteoblast Growth and Osseointegration

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Abstract:

ZnO nanoflowers prepared by a solution‐based hydrothermal growth method result in effective osteoblast growth with higher DNA content, ALP activity, and adhesion strength than those on ZnO film. Furthermore, ZnO nanoflowers are tightly osseointegrated into the regenerated bones. The approach for fabricating nanoflower structures on biomaterial surfaces can be successfully exploited for various bone tissue engineering applications.

Document Type: Communications

DOI: http://dx.doi.org/10.1002/adma.201002255

Affiliations: 1: Department of Material Science and Engineering, Pohang University of Science and Technology (POSTECH), San 31, Hyoja-dong, Nam-gu, Pohang, Kyungbuk, 790–784 (Korea) 2: National CRI Center for Semiconductor Nanorods, Department of Physics and Astronomy, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, 151–742 (Korea)

Publication date: November 16, 2010

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