Focal extramedullary haematopoiesis of the spleen: unusual MR appearance with pathological correlation

Authors: WANG, C-W; YU, C-Y; PENG, Y-J; WANG, C-Y; CHANG, W-C; HUANG, G-S

Source: British Journal of Radiology, Volume 81, Number 968, August 2008 , pp. e211-e214(4)

Publisher: British Institute of Radiology

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Abstract:

We report the unusual MR appearance of focal extramedullary haematopoiesis (EMH) of the spleen in a 72-year-old man with thrombocytopenia. Variable MR signal characteristics of EMH, which depend upon the amount of fat and the level of haematopoietic activity, have been described previously. We believe, however, that the delayed central enhancement of EMH on MRI findings was exceptional and has not been reported previously. After pathological investigation and correlation, we believe that the central zone containing hypocellular collagenous bundles may account for this specific enhancement.

Document Type: Case report

DOI: http://dx.doi.org/10.1259/bjr/13962743

Publication date: 2008-08-01