Haemodynamic parameters of the hepatic artery and vein can detect liver metastases: assessment using contrast-enhanced ultrasound

Authors: ZHOU, J H; LI, A H; CAO, L H; JIANG, H H; LIU, L Z; PEI, X Q; HAN, F

Source: British Journal of Radiology, 1 February 2008, vol. 81, no. 962, pp. 113-119(7)

Publisher:

Buy & download fulltext article:

The full text article is temporarily unavailable.

We apologise for the inconvenience. Please try again later.

Abstract:

This study was to assess the changes in the haemodynamic parameters of the hepatic artery and vein in the diagnosis of liver metastases by contrast-enhanced ultrasound (CEUS). 52 patients with proven liver metastases (patient group) and 23 normal volunteers (control group) were recruited in this study. Each subject was administered an intravenous bolus injection of SonoVue (0.6 ml). The arrival time in the hepatic artery (AT HA), time to peak in the hepatic artery (TTP HA), peak intensity of the hepatic artery (PI HA), arrival time in the hepatic vein (AT HV), time to peak in the hepatic vein (TTP HV) and peak intensity of the hepatic vein (PI HV) were measured with the use of time–intensity curve software. The hepatic artery to vein transit time (HAVTT) was calculated as the difference between the arrival times in the hepatic artery and the hepatic vein. AT HA, TTP HA, AT HV, TTP HV and HAVTT in the patient group were significantly shorter than those of the control group (P<0.01). PI HA and PI HV in the patient group were significantly higher than those of the control group (P<0.01).These results suggest that CEUS assessment of changes in the haemodynamic parameters of the hepatic artery and vein help to diagnose liver metastases. This functional imaging technique may contribute to the early detection of micrometastases in the liver.

Document Type: Research Article

DOI: http://dx.doi.org/10.1259/bjr/25294912

Publication date: February 1, 2008

Related content

Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content

Text size:

A | A | A | A
Share this item with others: These icons link to social bookmarking sites where readers can share and discover new web pages. print icon Print this page