Current Development in Tissue-Engineered Vascular Grafts

Authors: Tsatsaris, Athanasios; Perrea, Despina

Source: Vascular Disease Prevention, Volume 4, Number 4, November 2007 , pp. 333-334(2)

Publisher: Bentham Science Publishers

Buy & download fulltext article:

Price: $63.10 plus tax (Refund Policy)

Abstract:

Vascular tissue engineering has been hailed as a breakthrough in reconstructive vessel surgery. The traditional method includes either vessel substitution with an artificial graft or an autologous compatible tissue. For artificial grafts, some limitations are inevitable (e.g. thrombotic complications) and they cannot be used in substitution of small-caliber arterial vessels. On the other hand, the use of autologous donor-vessels is often restricted due to concomitant disease. The main aim of vascular tissue engineering is to provide biological artery substitutes by combining cellular components with biodegradable scaffolds. In this review, current approaches to vascular tissue engineering and the possible involvement of specific gene expression are discussed.

Keywords: Vascular; tissue; engineering; graft; clone-graft

Document Type: Research article

Publication date: 2007-11-01

More about this publication?

Vascular Disease Prevention publishes reviews as well as original papers to update all those concerned with this topic at the clinical or scientific level. In addition to clinically relevant topics, we consider reviews and original papers dealing with the more scientific aspects of vascular disease prevention. This includes the evaluation of emerging vascular risk factors, research dealing with the pathogenesis of atherosclerosis and the investigation of new treatment options both at the clinical and scientific level (e.g. epidemiology, patient-based studies, experimental models, in vitro experiments or molecular research). Therefore, another function of Vascular Disease Prevention is to bridge the gap between clinical practice and ongoing laboratory-based research.

In particular, we welcome critical reviews and comments on recent trials. This is a topic that requires regular updates because of the large number of trials published every year.

Debates are encouraged in the correspondence section of this journal.
The editorial structure of Vascular Disease Prevention is set up with the aim of dealing with the submitted material as rapidly as possible. Specialist editors will provide a more expert and rapid assessment unlike a more centralized editorial structure.

Current Development in Tissue-Engineered Vascular Grafts

Buy & download fulltext article:

Tools

Key

Text size:

Useful pages