Lifestyle Changes and Pharmacological Risk Factor Modification for Effective Vascular Disease Prevention

Author: Debabrata Mukherjee1

Source: Vascular Disease Prevention, Volume 1, Number 3, November 2004 , pp. 219-223(5)

Publisher: Bentham Science Publishers

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Abstract:

The most common symptom of patients with peripheral arterial disease [PAD] is intermittent claudication. Symptomatic peripheral vascular disease carries at least a 30% risk of death within five years and almost 50% within 10 years, primarily due to myocardial infarction [60%] or stroke [12%]. Lifestyle modification should be an integral component of secondary preventive therapy and complete cessation of tobacco use and regular exercise should be recommended for all patients. Lifestyle changes are also important in addressing / modifying the risk factors for PAD. Intensive pharmacological risk factor modification is another important part of the management of PAD.

Keywords: atherosclerosis; peripheral arterial disease; intermittent claudication; hypercholesterolemia; diabetes mellitus; thrombosis

Document Type: Review article

DOI: 10.2174/1567270043404926

Affiliations: 1: Division of Cardiology University of Michigan Health System University Hospital, TC B1 226 1500 E Medical Center Drive Ann Arbor, Michigan 48103 - 0311, USA.

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