Lifestyle Changes and Pharmacological Risk Factor Modification for Effective Vascular Disease Prevention

Author: Debabrata Mukherjee

Source: Vascular Disease Prevention, Volume 1, Number 3, November 2004 , pp. 219-223(5)

Publisher: Bentham Science Publishers

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Abstract:

The most common symptom of patients with peripheral arterial disease [PAD] is intermittent claudication. Symptomatic peripheral vascular disease carries at least a 30% risk of death within five years and almost 50% within 10 years, primarily due to myocardial infarction [60%] or stroke [12%]. Lifestyle modification should be an integral component of secondary preventive therapy and complete cessation of tobacco use and regular exercise should be recommended for all patients. Lifestyle changes are also important in addressing / modifying the risk factors for PAD. Intensive pharmacological risk factor modification is another important part of the management of PAD.

Keywords: atherosclerosis; peripheral arterial disease; intermittent claudication; hypercholesterolemia; diabetes mellitus; thrombosis

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1567270043404926

Affiliations: 1: Division of Cardiology University of Michigan Health System University Hospital, TC B1 226 1500 E Medical Center Drive Ann Arbor, Michigan 48103 - 0311, USA.

Publication date: 2004-11-01

More about this publication?
  • Vascular Disease Prevention publishes reviews as well as original papers to update all those concerned with this topic at the clinical or scientific level. In addition to clinically relevant topics, we consider reviews and original papers dealing with the more scientific aspects of vascular disease prevention. This includes the evaluation of emerging vascular risk factors, research dealing with the pathogenesis of atherosclerosis and the investigation of new treatment options both at the clinical and scientific level (e.g. epidemiology, patient-based studies, experimental models, in vitro experiments or molecular research). Therefore, another function of Vascular Disease Prevention is to bridge the gap between clinical practice and ongoing laboratory-based research.

    In particular, we welcome critical reviews and comments on recent trials. This is a topic that requires regular updates because of the large number of trials published every year.

    Debates are encouraged in the correspondence section of this journal.
    The editorial structure of Vascular Disease Prevention is set up with the aim of dealing with the submitted material as rapidly as possible. Specialist editors will provide a more expert and rapid assessment unlike a more centralized editorial structure.
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