Synchrotron Radiation in Life Sciences
Abstract:Synchrotron Radiation (SR) presents itself as a “play-ground” with a large range of methods and techniques suitable to unveil the mysteries of life. Here we attempt to present a few of these methods that complement those employed in the home laboratory. SR diffraction, spectroscopy and imaging methods relevant to the atomic structure determination and characterization of the properties and function of chemical compounds and macromolecules of biological relevance, are introduced.
Keywords: Herceptin; Single-crystal diffraction; Synchrotron Radiation; cryogenic methods; crystal structure; detector technologies; high- pressure crystallography; imaging methods; macromolecular crystallography; muscles fiber diffraction; spectroscopy; wavelength; x-ray diffraction; x-ray imaging
Document Type: Research Article
Publication date: 2012-07-01
- Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.