Role of Hsp70 in Cancer Growth and Survival
Keywords: ATP-induced high-to-low affinity; ATPase; DnaK; Heat shock protein; Hsp70; apoptosis; cancer; cancer cells; housekeeping functions; inhibition; nucleotide-binding domain (NBD); phospholipases; structure; substrate binding domain
Document Type: Research Article
Affiliations: Department of Biomedical Sciences, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178.
Publication date: 2012-06-01
- Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.