Proprotein Convertase Subtilisin Kexin9 (PCSK9): A Novel Target For Cholesterol Regulation
Keywords: Hypercholesterolemia (ADH); PCSK9 inhibitors; Proprotein convertase subtilisin Kexin9 (PCSK9); cholesterol lowering agents; fluorogenic peptide; hypercholesterolemia; low density lipoprotein receptor; low density lipoproteincholesterol; lysosome compartments; trans Golgi network (TGN)
Document Type: Research Article
Affiliations: Chronic Disease Program, Regional Protein Chemistry Center, Ottawa Hospital Research Institute, 725 Parkdale Avenue, Ottawa, ON K1Y 4E9, Canada.
Publication date: 2012-06-01
- Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.