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This issue of Protein & Peptide Letters includes 13 papers contributed by members of the Editorial Advisory Board (EAB) of the journal. These individuals play an important role in reviewing submissions to the journal and in promoting PPL to their colleagues around the world. One of the 12 issues each year features papers from their laboratories. This issue deals with manuscripts that were submitted during 2011, but with peer review and revisions, the accepted papers are only being published now. We will work to improve the speed of the process in future EAB member issues.

First, Ajoy Basak's laboratory has presented a paper titled “Proprotein Convertase Subtilisin Kexin9 (PCSK9): A Novel Target For Cholesterol Regulation”. This is a member of the mammalian subtilase family and is involved in degradation of the low density lipoprotein receptor. This work is important in the potential development of a new target for cholesterol lowering drugs.

The second paper is from the laboratory of David Phoenix titled “Effect of Amidation on the Antimicrobial Peptide Aurein 2.5 from Australian Southern Bell Frogs”. In addition to demonstrating a 2.5-fold enhancement of activity against Klebsiella pneumonia by the C-terminally amidated peptide, this paper explores the surface properties, helical content, and monolayers using Langmuir techniques.....
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Document Type: Research Article

Publication date: 01 June 2012

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  • Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.
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