A Reporter Platform for the Monitoring of In Vivo Conformational Changes in AcrB
Keywords: Disulfide trapping; Methicillin-resistant Staphylococcus aureus (MRSA); circular dichroism (CD); conformational changes; efflux pump; efflux pumps; fluorescence intensity; fluorescent labeling; gel electrophoresis; minimum inhibitory concentrations; multidrug resistance (MDR); mutagenesis; periplasmic domain; plasmids; prokaryotic cells; protein tertiary; quaternary structures; radioactive probes
Document Type: Research Article
Publication date: 01 September 2011
- Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.