3D-QSAR Study on a Series of Bcl-2 Protein Inhibitors Using Comparative Molecular Field Analysis
Keywords: 3D-QSAR; Bcl-2 protein; CoMFA; Comparative Molecular Field Analysis; GPCRs; Gasteiger-Huckel; HMLP; Partial Least Square; Sketch Molecule; Tripos force field; electrostatic field; inhibitors; leave-one-out; r2pred
Document Type: Research Article
Publication date: 2011-05-01
- Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.