Nucleolar Localization Signals of LIM Kinase 2 Function as a Cell- Penetrating Peptide
Keywords: 2-mercaptoethanol; 9-fluorenylmethoxycarbonyl solid phase synthesis; Blood-brain barrier (BBB); Cell Culture; Cell-Penetrating Peptide; Cell-penetrating peptides (CPPs); DMEM/F12; Drosophila melanogaster transcription factor; Drug delivery system (DDS); Dulbecco's modified Eagle's medium/F-12; Eagle's minimum essential; FITC-Labeled Peptides; Green fluorescence protein; HisTrap; Human iPS cells; LIM Kinase 2; LIM Kinase 2 (LIMK2); LIM Kinase 2 Function; LIM domain-containing protein kinase; LIMK2 NoLS-Conjugated Peptide; Nucleolar localization signal (NoLS); Peptide Synthesis; Protein transduction domain (PTD); Rink amide MBHA resin (Novabiochem); Von Hippel-Lindau; amphipathic peptides; baculovirus-silkworm expression system; blood-brain barrier; cell adhesion; cytoarchitecture; depolymerizing factor cofilin; endocytosis; fetal bovine serum; fibroblasts; gene expression; imidazole; induced pluripotent stem; medium (EMEM); nucleolar localization signal; nucleolar translocation signal; pM15; phosphorylation; proteoglycans; reverse-phase high performance liquid chromatography (HPLC; streptomycin; transactivating protein; β-karyopherin (kap) family
Document Type: Research Article
Publication date: 2010-12-01
- Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.