Drastic Effects on Fibril Formation of Amyloid-β Peptides by the Addition of Amino Acid Residue Units to the Termini
Abstract:We report that the addition of amino acids to the amyloid peptide dramatically affected the structure and the rate of formation of amyloid fibrils. The attachment of three lysines to Aβ(10-35) gave the formation of remarkably long fibrils, while three glutamates resulted in a faster formation rate of the fibrils.
Document Type: Research Article
Publication date: 2010-04-01
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