Provider: Ingenta Connect Database: Ingenta Connect Content: application/x-research-info-systems TY - ABST AU - Seidler, Norbert W. AU - Eklund, Joshua D. TI - Interfacial Effects on the Conformation of Amyloid-Beta Peptide JO - Protein and Peptide Letters PY - 2009-02-01T00:00:00/// VL - 16 IS - 2 SP - 182 EP - 188 KW - fluorescence KW - Amyloid-beta KW - protein folding KW - interface KW - sevoflurane N2 - We examined the effects of air-water and water-sevoflurane interfaces on conformational properties of amyloid- β peptide (ABP). Fractions were extracted from sub-interfacial (air-water) and supra-interfacial (water-sevoflurane) layers and compared with aqueous bulk layers using fluorescence properties of ABP provided by a single tyrosine. The observations suggest that interfacial ABP may be more disordered than bulk ABP.





UR - https://www.ingentaconnect.com/content/ben/ppl/2009/00000016/00000002/art00012 M3 - doi:10.2174/092986609787316324 UR - https://doi.org/10.2174/092986609787316324 ER -