Molecular Cloning and Expression of Several New Anopheles cracens Epsilon Class Glutathione Transferases
Abstract:Glutathione transferases, GSTs, are detoxification proteins that are found in most organisms. The acGSTE3-3 had the ability to conjugate 4-hydroxynonenal, a cytotoxic lipid peroxidation product. Although other Epsilon GSTs showed roles in insecticide metabolism, the acGSTE3-3 appeared to have a major role in detoxifying lipid peroxidation products conferring protection against oxidative damage.
Document Type: Research Article
Publication date: January 1, 2009
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