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T and B-cell Epitopes Prediction of Iranian Saffron (Crocus sativus) Profilin by Bioinformatics Tools

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Abstract:

Plant profilins form a well-known panallergen family responsible for cross-sensitization between plant foods and pollens. We sought to map T and B-cell epitopes on the Iranian Crocus sativus profilin by bioinformatics tools. The predicted peptides are useful for further vaccine development.





Keywords: Bioinformatics; Crocus sativus; Epitope; Profilin

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/092986608783744270

Publication date: March 1, 2008

More about this publication?
  • Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.
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