@article {Franz:2008:0929-8665:43, title = "Detection of a -Carboxy-Glutamate as Novel Post-Translational Modification of Human Transthyretin", journal = "Protein and Peptide Letters", parent_itemid = "infobike://ben/ppl", publishercode ="ben", year = "2008", volume = "15", number = "1", publication date ="2008-01-01T00:00:00", pages = "43-46", itemtype = "ARTICLE", issn = "0929-8665", url = "https://www.ingentaconnect.com/content/ben/ppl/2008/00000015/00000001/art00008", doi = "doi:10.2174/092986608783330297", keyword = "γ-Carboxy-glutamate, human transthyretin, cerebrospinal fluid, two-dimensional gel electrophoresis, moyamoya disease, post-translational modification", author = "Franz, Thomas and Ruggeberg, Sabrina and Horn, Peter and Li, Xinping and Vajkoczy, Peter", abstract = "During analysis of the proteome in the cerebrospinal fluid (CSF) of the Caucasian form of moyamoya disease (MMD), a novel post-translational modification of human transthyretin was observed. Two-dimensional electrophoresis and subsequent peptide sequencing with ESI-MS/MS were performed to discover the -carboxylation of the Glu-42 (Gla- 42). ", }