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Digital Coding of Amino Acids Based on Hydrophobic Index

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Analysis of amino acid sequences can provide useful insights into the tertiary structures of proteins and their biological functions. One of the critical problems in amino acid analysis is how to establish a digital coding system to better reflect the properties of amino acids and their degeneracy. Based on the hydrophobic index, a one-to-one relationship has been established between the amino acid sequence and the digital signal process. Such a “bridge” will make it possible to apply all the existing powerful methods in the signal processing area to analysis of the amino acid sequences.

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Keywords: Amino acid digital coding; hydrophobic index; pseudo amino acid composition; sequence analysis; signal process

Document Type: Research Article

Publication date: 2007-09-01

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  • Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.
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