Prediction of B Cell and T Cell Epitopes of DBLα Domain in Plasmodium falciparum Malaria Vaccine Candidate Var Gene
Abstract:P. falciparum encodes PfEMP-1 which is important in pathogenicity and virulence. We have analyzed the structure of the Duffy binding like (DBLα) domain of var genes and predicted the antigenic sites and T and B cell epitopes which present a highly variable picture with major implications in immune interactions and vaccine design.
Document Type: Research Article
Publication date: June 1, 2007
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