Variation in Resistance to Benzimidizole in Different Biocontrol Agents Based on Protein Sequence Homology

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Abstract:

Benzimidazole resistance in thirty isolates of the biocontrol agents was studied with reference to specific mutations in the β-tubulin genes. Our results suggest that apart from the correlation between specific mutations in the β-tubulin gene and variation in resistance, the overall ratio of polar and non-polar amino-acids may also play a vital role in conferring benzamidazole resistance to these fungi.





Keywords: benzamidazole; biocontrol agents; non-polar amino acids; polar amino acids

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/092986607780782821

Publication date: May 1, 2007

More about this publication?
  • Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.
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