Crystallization and Preliminary X-Ray Diffraction Studies of Two Myotoxic Lys49-Phospholipases A2 Complexed with α-Tocopherol
Abstract:BnSP-7 and BnSP-6, two Lys49-phospholipase A2 isolated from Bothrops neuwiedi pauloensis snake venom, were co-crystallized with α-tocopherol and X-ray diffraction data were collected for both complexes (2.2 and 2.6 Å). A new "alternative" quaternary conformation for these two complexes compared with all other dimeric Lys49-PLA2 has been observed.
Document Type: Review Article
Affiliations: Departamento de Fisica e Biofísica, Instituto de Biociencias, UNESP, C. P. 510, CEP 18618-000, Botucatu-SP, Brazil;
Publication date: 2005-11-01
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