Content of the Hmg-17 Chromosomal Protein in Porcine Tissues
Abstract:HMG-17 proteins are nucleosomal proteins, implicated in control of chromatin structure and transcription, in a way that has not yet been fully understood. In this report, quantification of HMG-17 in porcine tissues was performed, by ELISA, using previously produced and characterized specific rabbit anti- HMG-17 antibodies. Our results showed high levels of HMG-17 compared to the DNA and H1 content of the tissues (on the contrary to previous reports), and more specifically that there were 1.7 molecules of HMG-17 per molecule of histone H1.
Document Type: Review Article
Affiliations: Laboratory of Biological Chemistry, and Department of Forensic Medicine and Toxicology, Medical School, University of Ioannina, 451 10 Ioannina, Greece.
Publication date: 2004-12-01
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