Cytochrome C is a Hydrogen Peroxide Scavenger in Mitochondria
Authors: Wang Z-B.; Li M.; Zhao Y.; Xu J-X.
Source: Protein and Peptide Letters, Volume 10, Number 3, June 2003 , pp. 247-253(7)
Publisher: Bentham Science Publishers
Abstract:
The ability of succinate-cytochrome c reductase (SCR) reduced cytochrome c to scavenge H2O2 was investigated. H2O2, whether added or produced by SCR, was efficiently removed when cytochrome c was reduced by SCR. On the other hand, ferrocytochrome c underwent re-oxidization when H2O2 was added. Thus, these results indicate that cytochrome c reduced by succinate-cytochrome c reductase has the ability to regulate H2O2 in mitochondria.
Keywords: cytochrome; hydrogen peroxide; mitochondria; succinate-cytochrome c reductase
Language: English
Document Type: Review article
DOI: 10.2174/0929866033479013

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