Synthesis of Alkyl and Aryl Esters of N-Protected β-Homoamino Acids from N-Protected α-Aminodiazoketones
A simple and concomitant esterification method for the synthesis of methyl, ethyl, t-butyl, benzyl, and 9-fluorenylmethyl esters of Fmoc- / Boc- / Z-β-homoamino acids employing Fmoc- / Boc- / Z-α- aminodiazoketones by Wolff rearrangement is described. The method offers good yield with purity.
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Document Type: Review Article
Publication date: 2002-12-01
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