Modeling The Hierarchical Protein Folding Using Clustering Monte-Carlo Algorithm

Authors: Yesylevskyy S.O.; Demchenko A.P.

Source: Protein and Peptide Letters, Volume 8, Number 6, December 2001 , pp. 437-442(6)

Publisher: Bentham Science Publishers

Abstract:

A new modification of Monte-Carlo algorithm was suggested for the simulation of hierarchical protein folding. When applied to 2D lattice model of 12-member peptide this method allows observing complex kinetic folding behavior with the formation of clustered intermediates.

Keywords: HIERARCHICAL PROTEIN FOLDING; CLUSTERING MONTE-CARLO ALGORITHM; protein folding; Monte-Carlo simulations; lattice models; hierarchical cluster formation

Language: English

Document Type: Review article

DOI: http://dx.doi.org/10.2174/0929866013409166

Publication date: 2001-12-01

• Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.

• In this: publication
• By this: publisher
• In this Subject: Anatomy & Physiology
• By this author: Yesylevskyy S.O. ;  Demchenko A.P.

Website © Publishing Technology. Article copyright remains with the publisher, society or author(s) as specified within the article.

• Terms and conditions
• Privacy policy
• Information for advertisers