Conformation of Di-N-Propyl Glycine Residue in a Glycine Rich Peptide Sequence

Authors: Bhargava K.; Rao R.Balaji

Source: Protein and Peptide Letters, Volume 8, Number 4, August 2001 , pp. 307-315(9)

Publisher: Bentham Science Publishers

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Abstract:

The peptide Boc-(Gly-Dpg-Gly)3-OBzl (I) has been synthesized to examine the conformational preferences of Dpg residues in a peptide sequence rich in glycine, which is known to be a poor helix promoter. The detailed NMR studies revealed that peptide (I) adopts a helical conformation in CDCl3.

Keywords: Propyl Glycine; Glycine Rich Peptide

Language: English

Document Type: Review article

DOI: 10.2174/0929866013409346

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