Characteristics of a New Antifungal Protein from Ginkgo biloba L.

Authors: Huang H.; Xu J-f.; Gong Z-z.

Source: Protein and Peptide Letters, Volume 8, Number 3, June 2001 , pp. 209-216(8)

Publisher: Bentham Science Publishers

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Abstract:

A new antifungal protein, named as GAFP-1, was purified from leaves of Ginkgo biloba L. Its Molecular weight identified by mass spectrometry is 25988.0 Da and pI is 4.3. The analysis of amino acids composition showed it has high percentages of Gly and Glu / Gln. The 15 N-terminal amino acid residues of GAFP-1 were determined. GAFP-1 could inhibit the hyphal growth of P. sasakii Ito, the IC50 towards P.sasakii Ito is 250micro gram / ml. GAFP-1 has chitinase activity, the optimal pH and temperature being 5.0 and 50 C.

Keywords: ANTIFUNGAL PROTEIN; acetylglucosamine; GAFP-1

Language: English

Document Type: Review article

DOI: http://dx.doi.org/10.2174/0929866013409544

Publication date: 2001-06-01

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Protein & Peptide Letters publishes short papers in all important aspects of protein and peptide research, including structural studies, recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, drug design etc. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallisation, and preliminary structure determinations of biologically important proteins are acceptable. Purely theoretical papers are also acceptable provided they provide new insight into the principles of protein/peptide structure and function.