Bacterial Citrate Siderophores

Author: Budzikiewicz, H.

Source: Mini-Reviews in Organic Chemistry, Volume 2, Number 2, April 2005 , pp. 119-124(6)

Publisher: Bentham Science Publishers

Buy & download fulltext article:

Price: $63.10 plus tax (Refund Policy)

Abstract:

Soil bacteria as well as those infecting other organisms have developed systems to secure iron necessary for their metabolism which is generally not available in its free ionic form. As one of the possible strategies they learnt to produce secondary metabolites able to bind Fe3+ as water soluble complexes, so-called siderophores. A rather small group is based on citric acid. One of the ligand sites is the central C(OH)COOH unit, the two additional ones are carried by substituents bound to one or both of the terminal carboxyl groups. A survey will be presented.

Keywords: Iron metabolism; siderophores; citric acid derivatives

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1570193053544436

Affiliations: 1: Institut fur Organische Chemie, Universitat zu Koln, Greinstr. 4, 50939 Koln, Germany.

Publication date: 2005-04-01

More about this publication?

Mini-Reviews in Organic Chemistry publishes original reviews on all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition, and physical organic chemistry. The emphasis will be on publishing quality papers very rapidly. Mini-reviews will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts.

The journal is essential reading to all organic chemists in both academia and industry.