Currently Available Drugs for the Treatment of Obesity: Sibutramine and Orlistat

Authors: Chaput, J.-P.¹; St-Pierre, S.¹; Tremblay, A.¹

Source: Mini Reviews in Medicinal Chemistry, Volume 7, Number 1, January 2007 , pp. 3-10(8)

Publisher: Bentham Science Publishers

Abstract:

The currently available drugs for long-term treatment of obesity are sibutramine and orlistat. They have been shown to be able to induce significant weight loss, with important co-morbidity reduction, allowing the maintenance of reduced body weight for at least 1-2 years. Cardiostimulating and gastrointestinal adverse effects are however not negligible.

Keywords: Pharmacotherapy; sibutramine; orlistat; body weight; fat; energy balance; physical activity; diet

Document Type: Research article

DOI: 10.2174/138955707779317849

Affiliations: 1: Division of Kinesiology (PEPS), Laval University, Sainte-Foy, Québec, Canada, G1K 7P4.

Links for this article

http://www.ingentaconnect.com/ben/mrmc/2007/00000007/00000001/art00002
http://openurl.ingenta.com/content?genre=article&issn=1389-5575&volume=7&issue=1&spage=3&epage=10
http://dx.doi.org/10.2174/138955707779317849