Polyunsaturated Fatty Acids and Neurological Diseases

Authors: Salvati, S.¹; Attorri, L.¹; Di Benedetto, R.¹; Di Biase, A.¹; Leonardi, F.¹

Source: Mini Reviews in Medicinal Chemistry, Volume 6, Number 11, November 2006 , pp. 1201-1211(11)

Publisher: Bentham Science Publishers

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Abstract:

This review summarizes the knowledge of the role of dietary PUFAs, especially ω-3, on normal brain function. Furthermore, it reports the evidence pointing to potential mechanisms of ω-3 fatty acids in development of neurological disorders and efficacy of their supplementation in terms of symptom management.

Keywords: Docosahexaenoic acid; eicosapentaenoic acid; arachidonic acid; neurodegenerative diseases; Alzheimer's disease; Multiple sclerosis; Depression; Parkinson's disease

Document Type: Research article

DOI: 10.2174/138955706778742740

Affiliations: 1: Department of Food,Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy.

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