Focus on Recent Approaches for the Development of New NO-Donors

Authors: A. Gasco; R. Fruttero; B. Rolando

Source: Mini Reviews in Medicinal Chemistry, Volume 5, Number 2, February 2005 , pp. 217-229(13)

Publisher: Bentham Science Publishers

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Abstract:

Recent research developments in the field of NO-donor compounds have concerned conjugation of NO-donor moieties with antioxidant groups, NO-donor targeting, design of NO-donor hybrid drugs and of NOdelivery systems. These new approaches are illustrated and discussed through selected examples.

Keywords: nitric oxide; no-donors; no-donor antioxidants; no-donor targeting; drug/no-donor hybrids; no-delivery systems

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1389557053402684

Affiliations: 1: Dipartimento di Scienza e Tecnologia del Farmaco, Via P. Giuria, 9 - 10125 Torino - Italy.

Publication date: 2005-02-01

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The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

The scope of Mini-Reviews in Medicinal Chemistry will cover all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.