Recent Advances in the Development of Phytoestrogens and Derivatives: An Update of the Promising Perspectives in the Prevention of Postmenopausal Diseases

Authors: Jacquot Y.; Rojas C.; Refouvelet B.; Robert J.F.; Leclercq G.; Xicluna A.

Source: Mini Reviews in Medicinal Chemistry, Volume 3, Number 5, August 2003 , pp. 387-400(14)

Publisher: Bentham Science Publishers

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Abstract:

Phytoestrogens constitute a promising alternative in the treatment of diseases associated with menopause. Nevertheless, the lack of data concerning their pharmacology and their toxicology requires use precautions. After reminding the pharmacology of estrogen receptors, this review outlines the estrogenicity and the therapeutic potentialities of phytoestrogens according to their structure.

Keywords: phytoestrogens; estrogen receptor; menopause; pharmacology; therapeutic; structure; sar

Document Type: Review article

DOI: 10.2174/1389557033488006

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