Recent Advances in the Development of Phytoestrogens and Derivatives: An Update of the Promising Perspectives in the Prevention of Postmenopausal Diseases

Authors: Jacquot Y.; Rojas C.; Refouvelet B.; Robert J.F.; Leclercq G.; Xicluna A.

Source: Mini Reviews in Medicinal Chemistry, Volume 3, Number 5, August 2003 , pp. 387-400(14)

Publisher: Bentham Science Publishers

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Abstract:

Phytoestrogens constitute a promising alternative in the treatment of diseases associated with menopause. Nevertheless, the lack of data concerning their pharmacology and their toxicology requires use precautions. After reminding the pharmacology of estrogen receptors, this review outlines the estrogenicity and the therapeutic potentialities of phytoestrogens according to their structure.

Keywords: phytoestrogens; estrogen receptor; menopause; pharmacology; therapeutic; structure; sar

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1389557033488006

Publication date: 2003-08-01

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The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

The scope of Mini-Reviews in Medicinal Chemistry will cover all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.