Daphnane-Type Diterpene Orthoesters and their Biological Activities

Authors: He W.; Cik M.; Appendino G.; Puyvelde L.Van; Leysen J.E.; Kimpe N.De

Source: Mini Reviews in Medicinal Chemistry, Volume 2, Number 2, April 2002 , pp. 185-200(16)

Publisher: Bentham Science Publishers

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Abstract:

Daphnane orthoesters are the active ingredients of plant remedies from the Western, Chinese and African traditional medicine, and have provided important tools to investigate medicinally relevant processes like tumour promotion, apoptosis, neurotrophism, and VR1 activation. The occurrence, biological activity, and molecular pharmacology of these compounds will be reviewed.

Keywords: Daphnane-Type; Diterpene Orthoesters

Language: English

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1389557024605492

Publication date: 2002-04-01

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The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

The scope of Mini-Reviews in Medicinal Chemistry will cover all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.