Gas Chromatographic Determination of Prostaglandins

Authors: Baranowski R.; pacha K.

Source: Mini Reviews in Medicinal Chemistry, Volume 2, Number 2, April 2002 , pp. 135-144(10)

Publisher: Bentham Science Publishers

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Abstract:

Progress in separation and detection of prostaglandins and the other metabolites of arachidonic acid by means of GC-ECD, GC-MS, and GC-MS-MS in the course of the past fifteen years was reviewed. One discussed the problems of sample preparation, selection of proper chromatographic conditions, and detection modes available. Finally, applications of the methods developed to detection and quantification of prostanoids in biological material was presented.

Keywords: Gas Chromatographic

Language: English

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1389557024605465

Publication date: 2002-04-01

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The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

The scope of Mini-Reviews in Medicinal Chemistry will cover all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.