Towards Alzheimer's Disease Vaccination

Author: Solomon B.

Source: Mini Reviews in Medicinal Chemistry, Volume 2, Number 1, February 2002 , pp. 85-92(8)

Publisher: Bentham Science Publishers

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Abstract:

Active and passive immunization against fibrillar bgr-amyloid of various mice models of Alzheimer's disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-bgr-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimer's disease.

Keywords: Alzheimers Disease; EFRH-phage; Poly-L-lysine

Language: English

Document Type: Review article

DOI: 10.2174/1389557023406575

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