Alzheimer's Disease: Targets For Drug Development

Author: Larner A.J.

Source: Mini Reviews in Medicinal Chemistry, Volume 2, Number 1, February 2002 , pp. 1-9(9)

Publisher: Bentham Science Publishers

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Abstract:

The numerous advances in the understanding of the neurobiology of Alzheimer's disease in the past 15 years have suggested many new potential targets for therapeutic intervention. This article gives a broad overview of the spectrum of targets for AD treatment, with particular emphasis on amyloid bgr -peptides and tau protein.

Keywords: Alzheimers Disease; Amyloid Plaques; Tau Phosphorylation Inhibitors; Tau Aggregation Blockers; GLIAL CELLS

Language: English

Document Type: Review article

DOI: http://dx.doi.org/10.2174/1389557023406593

Publication date: 2002-02-01

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The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

The scope of Mini-Reviews in Medicinal Chemistry will cover all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.