Medicinal Chemistry

Assessment In Vitro of a Novel Therapeutic Strategy for Glioma, Combining Herpes Simplex Virus HSV1716-mediated Oncolysis with Gene Transfer and Targeted Radiotherapy
pp. 423-429(7)
Authors: Quigg, M.; Mairs, R. J.; Brown, S. M.; Harland, J.; Dunn, P.; Rampling, R.; Livingstone, A.; Wilson, L.; Boyd, M.

Interaction Field Based and Hologram Based QSAR Analysis of Propafenone-type Modulators of Multidrug Resistance
pp. 431-444(14)
Authors: Kaiser, D.; Smiesko, M.; Kopp, S.; Chiba, P.; Ecker, G. F.

Comparison of (+)- and (-)-Hemipalmitoylcarnitinium as Inhibitors of Hepatic Mitochondrial Carnitine Palmitoyltransferases in Diabetic Rats
pp. 445-453(9)
Authors: Savle, P. S.; Neptune, N. E.; Yang, Y.; Rouden, J. H.; Kite, B. L.; Sugandhi, E. W.; Macri, R. V.; Kashfi, K.; Gandour, R. D.

Free Energy Perturbation Calculations on Glucosidase-Inhibitor Complexes
pp. 455-460(6)
Authors: Ruiz, F. M.; Grigera, J. R.

Statin Attenuates High Glucose-Induced and Angiotensin II-Induced MAP Kinase Activity Through Inhibition of NAD(P)H Oxidase Activity in Cultured Mesangial Cells
pp. 461-468(8)
Authors: Yu, H. Y.; Inoguchi, T.; Nakayama, M.; Tsubouchi, H.; Sato, N.; Sonoda, N.; Sasaki, S.; Kobayashi, K.; Nawata, H.

ICG-001, A Novel Small Molecule Regulator of TCF/-Catenin Masakatsu Transcription
pp. 467-472(6)
Authors: Eguchi, M.; Nguyen, C.; Lee, S. C.; Kahn, M.

Enantioselective Synthesis and Preliminary Pharmacological Evaluation of the Enantiomers of Unifiram (DM232), a Potent Cognition-Enhancing Agent
pp. 473-480(8)
Authors: Martini, E.; Ghelardini, C.; Bertucci, C.; Dei, S.; Gualtieri, F.; Guandalini, L.; Manetti, D.; Scapecchi, S.; Teodori, E.; Romanelli, M. N.

New Features in Synthesis of Talampanel Related 2,3-Benzodiazepines
pp. 481-485(5)
Authors: Solyom, S.; Pallagi, I.; Abraham, G.; Kertesz, M.; Horvath, G.; Berzsenyi, P.

3D Solution Structure of [Tyr3]Octreotate Derivatives in DMSO: Structure Differentiation of Peptide Core Due to Chelate Group Attachment and Biologically Active Conformation
pp. 487-499(13)
Authors: Spyroulias, G. A.; Galanis, A. S.; Petrou, Ch.; Vahliotis, D.; Sotiriou, P.; Nikolopoulou, A.; Nock, B.; Maina, T.; Cordopatis, P.

N-Terminal Anthranoyl-Phenylalanine Derivatives as CCK1 Receptor Antagonists: The Final Approach
pp. 501-517(17)
Authors: Varnavas, A.; Lassiani, L.; Valenta, V.; Ciogli, A.; Gasparrini, F.; Mennuni, L.; Makovec, F.

Failure and Success in Modern Drug Discovery: Guiding Principles in the Establishment of High Probability of Success Drug Discovery Organizations
pp. 519-527(9)
Author: Rishton, G. M.