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Revisit: Eaton's Reagent Catalyzed Synthesis of Mono and Bis-Chalcone Derivatives

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Eaton's reagent efficiently catalyzed the Claisen-Schmidt condensation reaction of aryl aldehydes with aromatic and cyclic ketones under solvent free microwave irradiation conditions to afford mono and bis-chalcone derivatives. The present approach offers several advantages such as shorter reaction times, cleaner reactions, good yields, inexpensive reagent and mild reaction conditions.

Keywords: Aromatic aldehydes; aromatic ketone; chalcones; cyclic ketone; eaton's reagent; fused pyridines; iodine; pyrimidines; solvent-free; thiazines

Document Type: Research Article


Publication date: September 1, 2012

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  • Letters in Organic Chemistry publishes original letters on all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is placed on publishing quality papers very rapidly. Letters are processed rapidly and take full advantage of the Internet technology both for the submission and the review of the manuscripts.
    The journal is essential reading for all organic chemists both in academia and industry.

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