Skip to main content

Ligand-Free Cu-Catalyzed Cyanation of Aryl Halides with K4[Fe(CN)6] in Water

Buy Article:

$63.00 plus tax (Refund Policy)


A simple methodology for Cu-catalyzed cyanation of aryl halides with K4[Fe(CN)6] was developed with water as the solvent in conjunction with ligand-free Cu(OAc)2┬ĚH2O as the catalyst. The suggested methodology is applicable to cyanation of a wide range of aryl iodides and activated aryl bromides, and allows the catalyst to be reused six times with a very slight change in the catalytic activity.

Keywords: Cyanation; aryl halide; ligand-free catalyst; water solvent

Document Type: Research Article


Publication date: October 1, 2009

More about this publication?
  • Letters in Organic Chemistry publishes original letters on all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is placed on publishing quality papers very rapidly. Letters are processed rapidly and take full advantage of the Internet technology both for the submission and the review of the manuscripts.
    The journal is essential reading for all organic chemists both in academia and industry.

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more