Skip to main content

Synthesis of a Novel Heterocyclic System - Pyrimido[5',4':5,6]thiopyrano [2,3-b]indole

Buy Article:

$63.00 plus tax (Refund Policy)

Abstract:

An efficient protocol for the synthesis of pyrimido[5',4'p:5,6]thiopyrano[2,3-b]indoles by the cyclocondensation of 1,3-dihydro-2H-indole-2-thione with 6-chloropyrimidine-5-carbaldehydes has been developed. 4-Chloro-2- methylthiopyrimido[5',4':5,6]thiopyrano[2,3-b]indole was found to undergo smooth nucleophilic substitution with various nucleophiles to give 4-substituted pyrimido[5',4':5,6]thiopyrano[2,3-b]indoles.





Keywords: cyclocondensation; indoline-2-thione; nucleophilic substitution; pyrimidine-5-carbaldehydes; pyrimido[5',4':5,6] thiopyrano[2,3-b]indoles

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/157017809789869492

Publication date: October 1, 2009

More about this publication?
  • Letters in Organic Chemistry publishes original letters on all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is placed on publishing quality papers very rapidly. Letters are processed rapidly and take full advantage of the Internet technology both for the submission and the review of the manuscripts.
    The journal is essential reading for all organic chemists both in academia and industry.
ben/loc/2009/00000006/00000007/art00002
dcterms_title,dcterms_description,pub_keyword
6
5
20
40
5

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more