Asymmetric Synthesis of β-Aminosulfones Via the Enantioselective Hydrogenation of the Corresponding β-Ketosulfones
A series of β-aminosulfones were synthesized with high enantioselectivities via a new approach, which combines asymmetric hydrogenation of β-ketosulfones and Mitsunobu amination reaction of the corresponding β- hydroxysulfones with a significant high control of the stereochemistry.
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Document Type: Research Article
Publication date: 2008-04-01
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