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An Efficient Protocol for Henry Reaction Using Basic Ionic Liquid [bmIm]OH as Catalyst and Reaction Medium

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Henry reaction can be accelerated by basic ionic liquid 1-methyl-3-butylimidazolium hydroxide ([bmIm]OH) as catalyst and reaction medium with good yields in short time at room temperature. This strategy is general and works with a broad range of aldehydes. The recovered [bmIm]OH can be recycled with consistent activity.

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Keywords: 1-methyl-3-butylimidazolium hydroxide; Henry reaction; [bmIm]OH; basic ionic liquid; catalyst; recycle

Document Type: Research Article

Publication date: 2008-04-01

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  • Letters in Organic Chemistry publishes original letters on all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is placed on publishing quality papers very rapidly. Letters are processed rapidly and take full advantage of the Internet technology both for the submission and the review of the manuscripts.
    The journal is essential reading for all organic chemists both in academia and industry.
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