Regioselective Alkylation of Pyrrole with 2-Benzylidenemalononitriles Catalyzed by Cu(OTf)2
Copper triflate was used as catalyst for the addition of pyrrole to 2-benzylidenemalononitrile and its substituted derivatives. 2-Alkylated pyrrole derivatives were regioselectively obtained in mild reaction conditions. The addition reactions were found to be highly dependent on the substituents of the phenyl group.
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Document Type: Research Article
Publication date: 2008-04-01
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