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A Novel Approach for Ligand Promoted Palladium (II)-Catalyzed Suzuki Coupling of Aryl Iodides and Bromides with Arylboronic Acid in Aqueous Media

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A highly efficient, environmental friendly, palladium (II) catalyzed ligand promoted Suzuki reaction in aqueous phase was developed in short reaction time (4 - 5 h) at room temperature. The key for such a successful catalytic system was the use of suitable amount of co-solvent in the aqueous phase and reuse of palladium catalyst.

Keywords: Aqueous media; PdCl2[P(Ph)3]2catalyzed; aryl iodides and bromides; boronic acid; reuse of catalyst; suzuki-coupling reaction

Document Type: Research Article

Publication date: October 1, 2007

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  • Letters in Organic Chemistry publishes original letters on all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is placed on publishing quality papers very rapidly. Letters are processed rapidly and take full advantage of the Internet technology both for the submission and the review of the manuscripts.
    The journal is essential reading for all organic chemists both in academia and industry.

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