Bacteriorhodopsin Analogue from Indolic Chromophores

Authors: Prasanta Kumar Hota,; Anil Kumar Singh,

Source: Letters in Organic Chemistry, Volume 4, Number 4, June 2007 , pp. 300-305(6)

Publisher: Bentham Science Publishers

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Abstract:

A new analogue of bacteriorhodopsin (bR) was prepared by allowing bacterioopsin (bOP), the apo-protein of bR to interact with (2Z,4E)-3-chloro-5-(1H-indol-3-yl)-2,4-pentadienal as chromophore. It was characterised for its opsin shift, stability, light-induced pH change and fluorescence emission. Indolic aldehydes viz. 1H-indole-3-carboxaldehyde and (2Z,4E)-3-chloro-5-[1-(phenylsulfonyl)-1H-indol-3-yl]-2,4-pentadienal did not bind bOP.

Keywords: Bacteriorhodopsin; Indole; Bacteriorhodopsin analogues; Opsin shift; Rhodopsins

Document Type: Research article

Publication date: 2007-06-01

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