Michael Addition of Thiols to α-Enones: Is Any Catalyst Necessary?

Authors: Meciarova, Maria; Toma, Stefan

Source: Letters in Organic Chemistry, Volume 3, Number 10, October 2006 , pp. 794-797(4)

Publisher: Bentham Science Publishers

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Abstract:

Michael addition of thiophenol to chalcone was studied in different solvents. It was proved that reaction proceed very well in ionic liquids and chosen conventional solvents without any catalyst. It was also proved that reaction proceed well also with other thiols and other enones. Addition of selenophenol to chalcone in ethanol was also successful.

Keywords: Michael addition; ionic liquids; thiols; organocatalysts

Document Type: Research article

DOI: http://dx.doi.org/10.2174/157017806779025915

Affiliations: 1: Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, 842 15 Bratislava, Slovakia.

Publication date: 2006-10-01

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