Aza-Michael Additions on α, β-Unsaturated Esters Catalysed by Bismuth (III) Triflate in Conventional Chemistry and Under Microwave Irradiation

Authors: Monfray, Jeremy; Koskinen, Ari M.P.

Source: Letters in Organic Chemistry, Volume 3, Number 4, April 2006 , pp. 324-327(4)

Publisher: Bentham Science Publishers

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Abstract:

Aza-Michael additions are an easy way to prepare β-aminoesters. This reaction was investigated in the presence of catalytic amounts of bismuth (III) triflate under conventional and microwave irradiation conditions. It was shown that combination of both the catalyst and microwave irradiation under solvent-free conditions enhances the conjugate addition of amines to α,β-unsaturated esters.

Keywords: Bismuth triflate; michael addition; microwave synthesis; α,β-unsaturated ester

Document Type: Research article

DOI: http://dx.doi.org/10.2174/157017806776114496

Affiliations: 1: Laboratory of Organic Chemistry, Helsinki University of Technology, PO Box 6100, FI-02015 TKK, Finland.

Publication date: 2006-04-01

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