A One-Pot Synthesis of D-Ribonucleosides Using Natural Phosphate Doped with KI in HMDS

Authors: Lazrek, Hassan B.; Ouzebla, Driss; Rochdi, Abdellali; Redwane, Nezha; Vasseur, Jean-Jacques

Source: Letters in Organic Chemistry, Volume 3, Number 4, April 2006 , pp. 313-314(2)

Publisher: Bentham Science Publishers

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Potassium iodide supported on natural phosphate in HMDS was used as a promotor in the condensation of 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose with trimethylsilylated nucleobases, under mild conditions, to provide several D-ribonucleosides.

Keywords: Natural phosphate; nucleosides; potassium iodide

Document Type: Research Article

DOI: http://dx.doi.org/10.2174/157017806776114531

Affiliations: Faculty of Sciences Semlalia, 40000 Marrakesh Morocco.

Publication date: April 1, 2006

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